Altered skin microbiome, inflammation, and JAK/STAT signaling in Southeast Asian ichthyosis patients

Abstract Background Congenital ichthyosis (CI) is a collective group of rare hereditary skin disorders. Patients present with epidermal scaling, fissuring, chronic inflammation, and increased susceptibility to infections. Recently, there is increased interest in the skin microbiome; therefore, we hy...

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Main Authors: Minh Ho, Huynh-Nga Nguyen, Minh Van Hoang, Tien Thuy Thi Bui, Bao-Quoc Vu, Truc Huong Thi Dinh, Hoa Thi My Vo, Diana C. Blaydon, Sherif A. Eldirany, Christopher G. Bunick, Chi-Bao Bui
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-024-00603-x