Mitigation of intrahepatic cholestasis induced by 17α-ethinylestradiol via nanoformulation of Silybum marianum L.

Mitigation of intrahepatic cholestasis induced by 17α-ethinylestradiol via nanoformulation of Silybum marianum L.

Abstract Background Cholestasis is an important predisposing factor for hepatocyte damage, liver fibrosis, primary biliary cirrhosis, and even liver failure. Silybum marianum L. (SM) plant is used in teas or eaten in some countries due to its antioxidant and hepatoprotective properties. Because of i...

Full description

Bibliographic Details
Main Authors: Maha B. Salem, Dina Mostafa Mohammed, Olfat A. Hammam, Mohamed Elzallat
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Silybum Marianium L.
Nanoformulation
Intrahepatic cholestasis
Ethinylestradiol
Bile acid efflux
Inflammation
Online Access:https://doi.org/10.1186/s12906-024-04351-2

Internet

https://doi.org/10.1186/s12906-024-04351-2

Similar Items