Mechanical hierarchy in the formation and modulation of cortical folding patterns

Abstract The important mechanical parameters and their hierarchy in the growth and folding of the human brain have not been thoroughly understood. In this study, we developed a multiscale mechanical model to investigate how the interplay between initial geometrical undulations, differential tangenti...

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Bibliographic Details
Main Authors: Poorya Chavoshnejad, Liam Vallejo, Songyao Zhang, Yanchen Guo, Weiying Dai, Tuo Zhang, Mir Jalil Razavi
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40086-9