Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

Abstract Despite intensive basic scientific, translational, and clinical efforts in the last decades, glioblastoma remains a devastating disease with a highly dismal prognosis. Apart from the implementation of temozolomide into the clinical routine, novel treatment approaches have largely failed, em...

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Bibliographic Details
Main Authors: Leon Emanuel Schnöller, Daniel Piehlmaier, Peter Weber, Nikko Brix, Daniel Felix Fleischmann, Alexander Edward Nieto, Martin Selmansberger, Theresa Heider, Julia Hess, Maximilian Niyazi, Claus Belka, Kirsten Lauber, Kristian Unger, Michael Orth
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Radiation Oncology
Subjects:
Glioblastoma
Therapy resistance
Multi-level molecular data
Correlation analysis
Online Access:https://doi.org/10.1186/s13014-023-02241-4

Internet

https://doi.org/10.1186/s13014-023-02241-4

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