Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods.

Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods.

All of our current knowledge of African trypanosome metabolism is based on results from trypanosomes grown in culture or in rodents. Drugs against sleeping sickness must however treat trypanosomes in humans. We here compare the transcriptomes of Trypanosoma brucei rhodesiense from the blood and cere...

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Bibliographic Details
Main Authors: Julius Mulindwa, Kevin Leiss, David Ibberson, Kevin Kamanyi Marucha, Claudia Helbig, Larissa Melo do Nascimento, Eleanor Silvester, Keith Matthews, Enock Matovu, John Enyaru, Christine Clayton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5842037?pdf=render

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http://europepmc.org/articles/PMC5842037?pdf=render

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