The Alzheimer's Cell Atlas (TACA): A single‐cell molecular map for translational therapeutics accelerator in Alzheimer's disease

The Alzheimer's Cell Atlas (TACA): A single‐cell molecular map for translational therapeutics accelerator in Alzheimer's disease

Abstract Introduction Recent advances in generating massive single‐cell/nucleus transcriptomic data have shown great potential for facilitating the identification of cell type–specific Alzheimer's disease (AD) pathobiology and drug‐target discovery for therapeutic development. Methods We develo...

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Bibliographic Details
Main Authors: Yadi Zhou, Jielin Xu, Yuan Hou, Lynn Bekris, James B. Leverenz, Andrew A. Pieper, Jeffrey Cummings, Feixiong Cheng
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Alzheimer's disease
database
drug repurposing
network pathobiology
single‐cell
single‐nucleus
Online Access:https://doi.org/10.1002/trc2.12350

Internet

https://doi.org/10.1002/trc2.12350

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