Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats

The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33% increase in hepatic microsomal protein and a s...

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Bibliographic Details
Main Authors: S. Shefer, S. Hauser, E.H. Mosbach
Format: Article
Language:English
Published: Elsevier 1972-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520394384