mGluR-dependent synaptic plasticity in drug-seeking.

A primary feature of drug addiction is the compulsive use despite negative consequences. A general consensus is emerging on the capacity of addictive substances to co-opt synaptic transmission and synaptic plasticity in brain circuits which are involved in reinforcement and reward processing. A curr...

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Bibliographic Details
Main Authors: Camilla eBellone, Manuel eMameli
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00159/full