Sivelestat Alleviates Atherosclerosis by Improving Intestinal Barrier Function and Reducing Endotoxemia

Sivelestat Alleviates Atherosclerosis by Improving Intestinal Barrier Function and Reducing Endotoxemia

Emerging evidence suggests that atherosclerosis, one of the leading phenotypes of cardiovascular diseases, is a chronic inflammatory disease. During the atherosclerotic process, immune cells play critical roles in vascular inflammation and plaque formation. Meanwhile, gastrointestinal disorder is co...

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Bibliographic Details
Main Authors: Hezhongrong Nie, Qingquan Xiong, Guanghui Lan, Chunli Song, Xiaohong Yu, Lei Chen, Daming Wang, Tingyu Ren, Zeyan Chen, Xintong Liu, Yiwen Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerosis
sivelestat
intestinal permeability
endotoxemia
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.838688/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.838688/full

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