Total synthesis of justicidin B, justicidin E, and taiwanin C: A general and flexible approach toward the synthesis of natural arylnaphthalene lactone lignans

Total synthesis of justicidin B, justicidin E, and taiwanin C: A general and flexible approach toward the synthesis of natural arylnaphthalene lactone lignans

Lignans are widely present in traditional medicinal plants. Many natural arylnaphthalene lactone lignans (NALLs) isolated from the genera Justicia, Haplophyllum, and Phyllanthus possess interesting biological activities. Herein, we report a general strategy for the total synthesis of this kind of li...

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Bibliographic Details
Main Authors: Kai Wei, Yucui Sun, Yiren Xu, Wen Hu, Ying Ma, Yi Lu, Wen Chen, Hongbin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Chemistry
Subjects:
total synthesis
natural products
arylnaphthalene lactone lignans
Suzuki cross-coupling
cation-induced cyclization
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1103554/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.1103554/full

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