Recent Advances in Metal-Free Peptide Stapling Strategies
Protein–protein interactions (PPIs) pose challenges for intervention through small molecule drugs, protein drugs, and linear peptides due to inherent limitations such as inappropriate size, poor stability, and limited membrane penetrance. The emergence of stapled α-helical peptides presents a promis...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society
2024-06-01
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Series: | Chem & Bio Engineering |
Online Access: | https://doi.org/10.1021/cbe.3c00123 |