Effects of Intramolecular Distance between Amyloidogenic Domains on Amyloid Aggregation
Peptide/protein aggregation is implicated in many amyloid diseases. Some amyloidogenic peptides/proteins, such as those implicated in Alzheimer’s and Parkinson’s diseases, contain multiple amyloidogenic domains connected by “linker” sequences displaying high propensities to form turn structures. Rec...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/13/10/12169 |