Double-Blind Placebo-Controlled Pilot Investigation of the Safety of a Single Dose of Rapid-Acting Intranasal Insulin in Down Syndrome
Abstract Background Individuals with Down syndrome are likely to develop clinical and neuropathological brain changes resembling Alzheimer’s disease dementia by the ages of 35–40 years. Intranasal insulin is a potential treatment for neurodegenerative disease that has been shown to reduce amyloid pl...
Main Authors: | Michael Rosenbloom, Terry Barclay, Justin Johnsen, Lauren Erickson, Aleta Svitak, Maria Pyle, William Frey, Leah R. Hanson |
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Format: | Article |
Language: | English |
Published: |
Adis, Springer Healthcare
2020-02-01
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Series: | Drugs in R&D |
Online Access: | https://doi.org/10.1007/s40268-020-00296-2 |
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