Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest

Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest

ABSTRACTInitiation of bacterial DNA replication takes place at the origin of replication (oriC), a region characterized by the presence of multiple DnaA boxes that serve as the binding sites for the master initiator protein DnaA. This process is tightly controlled by modulation of the availability o...

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Bibliografische gegevens
Hoofdauteurs: Vanessa Muñoz-Gutierrez, Fabián A. Cornejo, Katja Schmidt, Christian K. Frese, Manuel Halte, Marc Erhardt, Alexander K. W. Elsholz, Kürşad Turgay, Emmanuelle Charpentier
Formaat: Artikel
Taal:English
Gepubliceerd in: American Society for Microbiology 2024-04-01
Reeks:mSystems
Onderwerpen:
Bacillus subtilis
replication
oriC
DnaA boxes
CRISPRi
translation
Online toegang:https://journals.asm.org/doi/10.1128/msystems.00221-24

Internet

https://journals.asm.org/doi/10.1128/msystems.00221-24

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