Site-specific phosphorylation of ZYG-1 regulates ZYG-1 stability and centrosome number

Summary: Spindle bipolarity is critical for genomic integrity. As centrosome number often dictates bipolarity, tight control of centrosome assembly is vital for faithful cell division. The master centrosome regulator ZYG-1/Plk4 plays a pivotal role in this process. In C. elegans, casein kinase II (C...

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Bibliographic Details
Main Authors: Jeffrey C. Medley, Rachel N. Yim, Joseph DiPanni, Brandon Sebou, Blake Shaffou, Evan Cramer, Colin Wu, Megan Kabara, Mi Hye Song
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024872