β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs.

Oocyte senescence alters the shape and function, thereby weakening the fertilization potential. Nicotinamide mononucleotide (NMN) reverses age-related dysfunctions in various organs. Studies had shown long-term administration of NMN reduced the physiological decline associated in aged mice and rever...

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Bibliographic Details
Main Authors: Leyi Li, Qinghe Han, Yurong Chen, Meng Zhang, Luyao Wang, Xinglan An, Sheng Zhang, Yanhui Zhai, Xiangpeng Dai, Bo Tang, Ziyi Li, Guanghong Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0291640&type=printable