The safety and efficacy of N-acetylcysteine as an augmentation in the treatment of obsessive-compulsive disorder in adults: a systematic review and meta-analysis of randomized clinical trials

The safety and efficacy of N-acetylcysteine as an augmentation in the treatment of obsessive-compulsive disorder in adults: a systematic review and meta-analysis of randomized clinical trials

BackgroundObsessive-compulsive disorder (OCD) ranks as the fourth most prevalent psychiatric disorder, with selective serotonin reuptake inhibitors (SSRIs) as its mainstay pharmacological treatment. However, approximately 40 to 60% of patients do not adequately respond to initial treatment, highligh...

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Bibliographic Details
Main Authors: Shayan Eghdami, Negin Eissazade, Mohsen Heidari Mokarar, Mahsa Boroon, Laura Orsolini, Mohammadreza Shalbafan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Psychiatry
Subjects:
acetylcysteine
obsessive-compulsive disorder
glutamate
systematic review
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1421150/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1421150/full

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