Astrocytes as critical players of the fine balance between inhibition and excitation in the brain: spreading depolarization as a mechanism to curb epileptic activity

Spreading depolarizations (SD) are slow waves of complete depolarization of brain tissue followed by neuronal silencing that may play a role in seizure termination. Even though SD was first discovered in the context of epilepsy research, the link between SD and epileptic activity remains understudie...

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Bibliographic Details
Main Authors: Rune Enger, Kjell Heuser
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Network Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnetp.2024.1360297/full