Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinoma

Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinoma

Abstract Background Chaperonin-containing tailless complex polypeptide 1 (TCP1) subunit 3 (CCT3) has tumor-promoting effects in lung adenocarcinoma (LUAD). This study aims to investigate the molecular mechanisms of CCT3 in LUAD oncogenesis. Methods The UALCAN databases, Human Protein Atlas (HPA) and...

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Bibliographic Details
Main Authors: Junfeng Huang, Bingqi Hu, Ying Yang, Huanhuan Liu, Xingyu Fan, Jing Zhou, Liwen Chen
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cancer
Subjects:
Lung adenocarcinoma
TCP1
CCT3
Immune cell infiltration
Biomarker
Online Access:https://doi.org/10.1186/s12885-023-10677-w

Internet

https://doi.org/10.1186/s12885-023-10677-w

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