Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin cytoskeleton, which are opposed by the cortical cytoskeleton of the interacting antigen-presenting cell. During an immune response, DCs undergo a maturation process that optimizes their ability to efficiently prim...

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Bibliographic Details
Main Authors: Daniel Blumenthal, Vidhi Chandra, Lyndsay Avery, Janis K Burkhardt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55995