Aversion-related effects of kappa-opioid agonist U-50488 on neural activity and functional connectivity between amygdala, ventral tegmental area, prefrontal cortex, hippocampus, and nucleus accumbens

Introduction: Among the various receptor systems in the brain, the opioid receptors have been the subject of extensive research due to their integral role in pain modulation, reward processing, and emotional regulation. The kappa-opioid receptor (KOR) system, in particular, stands apart due to its u...

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Bibliographic Details
Main Authors: Konstantin Y. Kalitin, Alexander A. Spasov, Olga Y. Mukha
Format: Article
Language:English
Published: Belgorod National Research University 2023-11-01
Series:Research Results in Pharmacology
Subjects:
Online Access:https://rrpharmacology.ru/index.php/journal/article/view/387/424