Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation

Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation

Abstract Background Cysteine-rich intestinal protein 1 (CRIP1) is highly expressed in human intestine and aberrantly expressed in several types of tumor. However, studies on CRIP1 are limited and its role on tumor development and progression remains controversial and elusive. Methods Immunohistochem...

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Bibliographic Details
Main Authors: Lanzhi Zhang, Rui Zhou, Weibin Zhang, Xueqing Yao, Weidong Li, Lijun Xu, Xuegang Sun, Liang Zhao
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cysteine-rich intestinal protein 1
Colorectal cancer
Apoptosis
Chemoresistant
FAS
Online Access:http://link.springer.com/article/10.1186/s13046-019-1117-z

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http://link.springer.com/article/10.1186/s13046-019-1117-z

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