Two-Dimensional and Spheroid-Based Three-Dimensional Cell Culture Systems: Implications for Drug Discovery in Cancer

Two-Dimensional and Spheroid-Based Three-Dimensional Cell Culture Systems: Implications for Drug Discovery in Cancer

The monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in replicating vital cell interactions seen in vivo, leading to a shift toward three-dimensional (3D) models. Although monolayers offer simplicity and cost-effectiveness, spheroids mimic cellular environments bette...

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Bibliografische gegevens
Hoofdauteurs: Anali del Milagro Bernabe Garnique, Natália Sudan Parducci, Lívia Bassani Lins de Miranda, Bruna Oliveira de Almeida, Leonardo Sanches, João Agostinho Machado-Neto
Formaat: Artikel
Taal:English
Gepubliceerd in: MDPI AG 2024-06-01
Reeks:Drugs and Drug Candidates
Onderwerpen:
cell cycle drugs
cytoskeleton drugs
monolayer
spheroids
3D cell culture
Online toegang:https://www.mdpi.com/2813-2998/3/2/24

Internet

https://www.mdpi.com/2813-2998/3/2/24

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