Sequence-dependent base pair stepping dynamics in XPD helicase unwinding

Helicases couple the chemical energy of ATP hydrolysis to directional translocation along nucleic acids and transient duplex separation. Understanding helicase mechanism requires that the basic physicochemical process of base pair separation be understood. This necessitates monitoring helicase activ...

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Bibliographic Details
Main Authors: Zhi Qi, Robert A Pugh, Maria Spies, Yann R Chemla
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00334