Dosimetry of [18F]TRACK, the first PET tracer for imaging of TrkB/C receptors in humans

Dosimetry of [18F]TRACK, the first PET tracer for imaging of TrkB/C receptors in humans

Abstract Background Reduced expression or impaired signalling of tropomyosin receptor kinases (Trk receptors) are found in a vast spectrum of CNS disorders. [18F]TRACK is the first PET radioligand for TrkB/C with proven in vivo brain penetration and on-target specific signal. Here we report dosimetr...

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Bibliographic Details
Main Authors: Alexander Thiel, Alexey Kostikov, Hailey Ahn, Youstina Daoud, Jean-Paul Soucy, Stephan Blinder, Carolin Jaworski, Carmen Wängler, Björn Wängler, Freimut Juengling, Shirin A. Enger, Ralf Schirrmacher
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Tropomyosin receptor kinases
Positron emission tomography
[18F]TRACK
Dosimetry
Online Access:https://doi.org/10.1186/s41181-023-00219-x

Internet

https://doi.org/10.1186/s41181-023-00219-x

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