Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells

Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells

Abstract Background Cell reprogramming is a promising avenue for cell-based therapies as it allows for the generation of multipotent, unipotent, or mature somatic cells without going through a pluripotent state. While the use of autologous cells is considered ideal, key challenges for their clinical...

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Main Authors: Jan-Eric Ahlfors, Ashkan Azimi, Rouwayda El-Ayoubi, Alexander Velumian, Ilan Vonderwalde, Cecile Boscher, Oana Mihai, Sarathi Mani, Marina Samoilova, Mohamad Khazaei, Michael G. Fehlings, Cindi M Morshead
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
drNPC
Direct reprogramming
Neural precursor cells
Neural stem cells
In vivo neurogenesis
In vivo remyelination
Online Access:http://link.springer.com/article/10.1186/s13287-019-1255-4

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http://link.springer.com/article/10.1186/s13287-019-1255-4

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