CoCUN, a Novel Ubiquitin Binding Domain Identified in N4BP1

CoCUN, a Novel Ubiquitin Binding Domain Identified in N4BP1

Ubiquitin binding domains (UBDs) are modular elements that bind non-covalently to ubiquitin and act as downstream effectors and amplifiers of the ubiquitination signal. With few exceptions, UBDs recognize the hydrophobic path centered on Ile44, including residues Leu8, Ile44, His68, and Val70. A var...

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Bibliographic Details
Main Authors: Ridvan Nepravishta, Federica Ferrentino, Walter Mandaliti, Anna Mattioni, Janine Weber, Simona Polo, Luisa Castagnoli, Gianni Cesareni, Maurizio Paci, Elena Santonico
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
ubiquitin-binding domains (UBDs)
nuclear magnetic resonance spectroscopy
cullin binding domain associating with NEDD8 (CUBAN)
KH And NYN domain containing (KHNYN)
neural precursor cell expressed developmentally downregulated gene 8 (NEDD8)
Online Access:https://www.mdpi.com/2218-273X/9/7/284

Internet

https://www.mdpi.com/2218-273X/9/7/284

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