Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model
Abnormal cellular and circuit excitability is believed to drive many core phenotypes in fragile X syndrome (FXS). The dentate gyrus is a brain area performing critical computations essential for learning and memory. However, little is known about dentate circuit defects and their mechanisms in FXS....
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/92563 |