Novel Pyropheophorbide Phosphatydic Acids Photosensitizer Combined EGFR siRNA Gene Therapy for Head and Neck Cancer Treatment

Novel Pyropheophorbide Phosphatydic Acids Photosensitizer Combined EGFR siRNA Gene Therapy for Head and Neck Cancer Treatment

This study combined two novel nanomedicines, a novel LCP Pyro PA photodynamic therapy (PDT) and LCP EGFR siRNA gene therapy, to treat head and neck cancer. A novel photosensitizer, pyropheophorbide phosphatydic acids (Pyro PA), was first modified into Lipid-Calcium phosphate nanoparticles named LCP...

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Bibliographic Details
Main Authors: Chia-Hsien Yeh, Juan Chen, Gang Zheng, Leaf Huang, Yih-Chih Hsu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
targeted delivery
head and neck cancer
nanoparticles
photodynamic therapy
Online Access:https://www.mdpi.com/1999-4923/13/9/1435

Internet

https://www.mdpi.com/1999-4923/13/9/1435

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