Allopurinol reduces antigen-specific and polyclonal activation of human T cells

Allopurinol is the most popular commercially available xanthine oxidase inhibitor and it is widely used for treatment of symptomatic hyperuricaemia, or gout. Although, several anti-inflammatory actions of allopurinol have been demonstrated in vivo and in vitro, there have been few studies on the act...

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Main Authors: Damián ePérez-Mazliah, María Cecilia Albareda, María Gabriela Alvarez, Bruno Edgardo Lococo, Graciela Luciana Bertocchi, Marcos ePetti, Rodolfo eViotti, Susana Adriana Laucella
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00295/full