Anti-Melanoma Effects of Miconazole: Investigating the Mitochondria Involvement

Miconazole is an antimycotic drug showing anti-cancer effects in several cancers. However, little is known on its effects in melanoma. A375 and SK-MEL-28 human melanoma cell lines were exposed to miconazole and clotrimazole (up to 100 mM). Proliferation, viability with MTT assay and vascular mimicry...

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Bibliographic Details
Main Authors: Francesca Scatozza, Maria Miriam Giardina, Carola Valente, Virginia Vigiano Benedetti, Antonio Facchiano
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/7/3589