S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood–Brain Barrier Damage

S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood–Brain Barrier Damage

Background: Ischemic stroke is the most common stroke incident. Sphingosine-1-phosphate (S1P) receptor 3 (S1PR3) is a member of the downstream G protein-coupled receptor family of S1P. The effect of S1PR3 on ischemic stroke remains elusive.Methods: We downloaded two middle cerebral artery occlusion...

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Bibliographic Details
Main Authors: Xuehui Fan, Hongping Chen, Chen Xu, Yingju Wang, Pengqi Yin, Meng Li, Zhanbin Tang, Fangchao Jiang, Wan Wei, Jihe Song, Guozhong Li, Di Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
ischemic stroke
S1PR3
blood–brain barrier
cerebral ischemia/reperfusion injury
WGCNA analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.834948/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.834948/full

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