Probabilistic modeling methods for cell-free DNA methylation based cancer classification
Abstract Background cfMeDIP-seq is a low-cost method for determining the DNA methylation status of cell-free DNA and it has been successfully combined with statistical methods for accurate cancer diagnostics. We investigate the diagnostic classification aspect by applying statistical tests and dimen...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-04-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-04651-9 |