Probabilistic modeling methods for cell-free DNA methylation based cancer classification

Abstract Background cfMeDIP-seq is a low-cost method for determining the DNA methylation status of cell-free DNA and it has been successfully combined with statistical methods for accurate cancer diagnostics. We investigate the diagnostic classification aspect by applying statistical tests and dimen...

Full description

Bibliographic Details
Main Authors: Viivi Halla-aho, Harri Lähdesmäki
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04651-9