GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil

GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil

IntroductionThe fMRI BOLD response to emotional stimuli highlighting the role of the medial prefrontal cortex (MPFC) has been thoroughly investigated. Recently, the relationship between emotion processing and GABA levels has been studied using MPFC proton magnetic resonance spectroscopy (1H-MRS). Ho...

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Bibliographic Details
Main Authors: Alexander Heinzel, Jörg Mauler, Hans Herzog, Frank Boers, Felix M. Mottaghy, Karl-Josef Langen, Jürgen Scheins, Christoph Lerche, Bernd Neumaier, Georg Northoff, N. Jon Shah
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neuroscience
Subjects:
simultaneous fMRI/PET
GABAA receptor
emotion
[11C]flumazenil
BOLD signal
binding potential
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1027697/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.1027697/full

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