Use of FLOSEAL® as a scaffold and its impact on induced neural stem cell phenotype, persistence, and efficacy

Use of FLOSEAL® as a scaffold and its impact on induced neural stem cell phenotype, persistence, and efficacy

Abstract Induced neural stem cells (iNSCs) have emerged as a promising therapeutic platform for glioblastoma (GBM). iNSCs have the innate ability to home to tumor foci, making them ideal carriers for antitumor payloads. However, the in vivo persistence of iNSCs limits their therapeutic potential. We...

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Bibliographic Details
Main Authors: Hunter N. Bomba, Abigail Carey‐Ewend, Kevin T. Sheets, Alain Valdivia, Morgan Goetz, Ingrid A. Findlay, Alison Mercer‐Smith, Lauren E. Kass, Simon Khagi, Shawn D. Hingtgen
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Bioengineering & Translational Medicine
Subjects:
fibrin
gelatin
glioblastoma
neural stem cell
scaffold
TRAIL
Online Access:https://doi.org/10.1002/btm2.10283

Internet

https://doi.org/10.1002/btm2.10283

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