7-nitroindazole, a selective neuronal nitric oxide synthase inhibitore in vivo, prevents kainate-induced intrahippocampal neurotoxicity

7-nitroindazole, a selective neuronal nitric oxide synthase inhibitore in vivo, prevents kainate-induced intrahippocampal neurotoxicity

We investigated the effects of 7-nitroindazole (7-NI), a selective neuronal nitric oxide synthase inhibitor in vivo, on nitrite concentration after kainic acid injection unilaterally into the CA3 region of the rat hippocampus. The accumulation of nitrite, the stable metabolite of NO, was measured by...

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Bibliographic Details
Main Authors: Radenović Lidija Lj., Selaković Vesna, Božić Biljana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2005-01-01
Series:Archives of Biological Sciences
Subjects:
7-nitroindazole
brain
glutamate receptors
hippocampus
kainate
neurological disorders
neuroprotection
neurotoxicity
nitric oxide
nitrite
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2005/0354-46640502075R.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2005/0354-46640502075R.pdf

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