OPTIMIZATION OF SOLID-PHASE SYNTHESIS OF POLYAMIDE NUCLEIC ACID MIMETICS WITH APPLICATION OF MALDI-TOF MASS-SPECTROMETRY
The solid-phase synthesis of a tetrameric model sequence of polyamide nucleic acid mimetics (PANAM) incorporating terminal chiral and charged unit was performed. As a result during the synthesis and cleavage from the resin the tendency of PANAM with the N-terminal negatively charged monomer to cycli...
Main Authors: | , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
MIREA - Russian Technological University
2013-02-01
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Series: | Тонкие химические технологии |
Subjects: | |
Online Access: | https://www.finechem-mirea.ru/jour/article/view/659 |