Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models

Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models

Introduction: Surgical 5/6 nephrectomy and adenine-induced kidney failure in rats are frequently used models of progressive renal failure. In both models, rats develop significant morphological changes in the kidneys and quantification of these changes can be used to measure the efficacy of prophyla...

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Bibliographic Details
Main Authors: Marcin Klapczynski, Gerard D Gagne, Sherry J Morgan, Kelly J Larson, Bruce E LeRoy, Eric A Blomme, Bryan F Cox, Eugene W Shek
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pathology Informatics
Subjects:
5/6 nephrectomy
adenine kidney model
digital pathology
digital slide
Genie
image analysis
rodent renal failure model
Online Access:http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2012;volume=3;issue=1;spage=20;epage=20;aulast=

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http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2012;volume=3;issue=1;spage=20;epage=20;aulast=

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