Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice

Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice

Abstract To investigate the protective efficacy and mechanism of ZF2001 (a protein subunit vaccine with conditional approval in China) to SARS-CoV-2 Delta variant-induced severe pneumonia, the lethal challenge model of K18-hACE2 transgenic mice was used in this study. An inactivated-virus vaccine at...

Full description

Bibliographic Details
Main Authors: Lianlian Bian, Yu Bai, Fan Gao, Mingchen Liu, Qian He, Xing Wu, Qunying Mao, Miao Xu, Zhenglun Liang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Virology Journal
Subjects:
ZF2001
Protection
SARS-CoV-2 Delta variant
K18-hACE2 mice
Online Access:https://doi.org/10.1186/s12985-022-01818-x

Internet

https://doi.org/10.1186/s12985-022-01818-x

Similar Items