Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice

Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice

Abstract To investigate the protective efficacy and mechanism of ZF2001 (a protein subunit vaccine with conditional approval in China) to SARS-CoV-2 Delta variant-induced severe pneumonia, the lethal challenge model of K18-hACE2 transgenic mice was used in this study. An inactivated-virus vaccine at...

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Bibliographic Details
Main Authors:	Lianlian Bian, Yu Bai, Fan Gao, Mingchen Liu, Qian He, Xing Wu, Qunying Mao, Miao Xu, Zhenglun Liang
Format:	Article
Language:	English
Published:	BMC 2022-05-01
Series:	Virology Journal
Subjects:	ZF2001 Protection SARS-CoV-2 Delta variant K18-hACE2 mice
Online Access:	https://doi.org/10.1186/s12985-022-01818-x

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