DNAscent v2: detecting replication forks in nanopore sequencing data with deep learning

Abstract Background Measuring DNA replication dynamics with high throughput and single-molecule resolution is critical for understanding both the basic biology behind how cells replicate their DNA and how DNA replication can be used as a therapeutic target for diseases like cancer. In recent years,...

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Bibliographic Details
Main Author: Michael A. Boemo
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07736-6