Positively charged nanocomplex modulates dendritic cell differentiation to enhance Th1 immune response

Positively charged nanocomplex modulates dendritic cell differentiation to enhance Th1 immune response

Most existing vaccines use activators that polarize the immune response to T-helper (Th) 2 response for antibody production. Our positively charged chitosan (Cs)-based nanocomplex (CNC) drives the Th1 response through unknown mechanisms. As receptors for the positively charged CNC are not determined...

Full description

Bibliographic Details
Main Authors: Yan-Wei Wu, Wan-Yu Wang, Yu-Hung Chen
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
Nanocomplex
Surface charge
Dendritic cell
Cell differentiation
Th1 response
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422002782

Internet

http://www.sciencedirect.com/science/article/pii/S2590006422002782

Similar Items