Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases
The mechanism by which DNA methylation might affect complex traits is not well understood. Here, the authors use Mendelian randomization to reveal a substantial role of transcript levels in mediating DNA methylation effects on complex traits and diseases.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35196-3 |