A retrospective multicenter study on clinical and serological parameters in patients with MuSK myasthenia gravis with and without general immunosuppression

A retrospective multicenter study on clinical and serological parameters in patients with MuSK myasthenia gravis with and without general immunosuppression

IntroductionMuscle-specific kinase (MuSK)- myasthenia gravis (MG) is caused by pathogenic autoantibodies against MuSK that correlate with disease severity and are predominantly of the IgG4 subclass. The first-line treatment for MuSK-MG is general immunosuppression with corticosteroids, but the effec...

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Bibliographic Details
Main Authors: Inga Koneczny, Marina Mané-Damas, Shenghua Zong, Sander De Haas, Saif Huda, Daan van Kruining, Jan Damoiseaux, Anna De Rosa, Michelangelo Maestri, Melania Guida, Peter Molenaar, Philip Van Damme, Andreas Fichtenbaum, Thomas Perkmann, Marc De Baets, Konstantinos Lazaridis, Vasiliki Zouvelou, Socrates Tzartos, Roberta Ricciardi, Mario Losen, Pilar Martinez-Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
MuSK myasthenia gravis
IgG4
corticosteroids
prednisolone
prednisone
IgG4 autoimmune disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1325171/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1325171/full

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