Targeting vascular disrupting agent-treated tumor microenvironment with tissue-penetrating nanotherapy

Abstract Cancer treatment with vascular disrupting agents (VDAs) causes rapid and extensive necrosis in solid tumors. However, these agents fall short in eliminating all malignant cells, ultimately leading to tumor regrowth. Here, we investigated whether the molecular changes in the tumor microenvir...

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Main Authors: Valeria Sidorenko, Pablo Scodeller, Ain Uustare, Ivan Ogibalov, Andrus Tasa, Olga Tshubrik, Liis Salumäe, Kazuki N. Sugahara, Lorena Simón-Gracia, Tambet Teesalu
格式: Article
語言:English
出版: Nature Portfolio 2024-07-01
叢編:Scientific Reports
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在線閱讀:https://doi.org/10.1038/s41598-024-64610-7