Method Development and Qualification of pH-Based CEX UPLC Method for Monoclonal Antibodies
Post-translational modifications (“PTMs”) in monoclonal antibodies (mAbs) contribute to charge variant distribution, which will affect biological efficacy and safety. For the characterization of mAbs, charge variants are used as a critical quality attributes for product quality, stability consistenc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-06-01
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| Series: | BioTech |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-6284/11/2/19 |