Cholinergic signaling exerts protective effects in models of sympathetic hyperactivity-induced cardiac dysfunction.

Cholinergic signaling exerts protective effects in models of sympathetic hyperactivity-induced cardiac dysfunction.

Cholinergic control of the heart is exerted by two distinct branches; the autonomic component represented by the parasympathetic nervous system, and the recently described non-neuronal cardiomyocyte cholinergic machinery. Previous evidence has shown that reduced cholinergic function leads to deleter...

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Bibliographic Details
Main Authors: Mariana Gavioli, Aline Lara, Pedro W M Almeida, Augusto Martins Lima, Denis D Damasceno, Cibele Rocha-Resende, Marina Ladeira, Rodrigo R Resende, Patricia M Martinelli, Marcos Barrouin Melo, Patricia C Brum, Marco Antonio Peliky Fontes, Robson A Souza Santos, Marco A M Prado, Silvia Guatimosim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081111?pdf=render

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http://europepmc.org/articles/PMC4081111?pdf=render

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