Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal

Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal

Neurotransmitter is released from presynaptic nerve terminals at fast-transmitting synapses by the action potential-gating of voltage dependent calcium channels (CaV), primarily of the CaV2.1 and CaV2.2 types. Entering Ca2+ diffuses to a nearby calcium sensor associated with a docked synaptic vesicl...

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Bibliographic Details
Main Authors: Christine A. Snidal, Qi Li, Brittany B. Elliott, Henry K.-H. Mah, Robert H. C. Chen, Sabiha R. Gardezi, Elise F. Stanley
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
presynaptic
calcium channel
synaptic vesicle tether
CaV2.1
P-type
channel C-terminal
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00127/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2018.00127/full

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