A mild catalyzed imino Diels-Alder reaction for the synthesis of N-(2-(o-tolyl)-1,2,3,4-tetrahydroquinoline-4-yl)formamide derivatives as regulators of Quorum Sensing in Pseudomonas aeruginosa

A mild catalyzed imino Diels-Alder reaction for the synthesis of N-(2-(o-tolyl)-1,2,3,4-tetrahydroquinoline-4-yl)formamide derivatives as regulators of Quorum Sensing in Pseudomonas aeruginosa

Bacterial resistance is one of the major global public health problems. In addition, virulence factors promoted multiple drug resistance through cell-to-cell communications by molecules within microbial communities, denominated Quorum Sensing (QS). The regulation of QS by small molecules appears as...

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Bibliographic Details
Main Authors: Leidy J. García Maza, Dayanna F. Orosco Flórez, Arturo René Mendoza Salgado, Wendy Rosales, Evelyn Mendoza-Torres, Carlos Mario Meléndez
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Antibacterial resistance
Quorum Sensing
Synthetic inhibitors
Tetrahydroquinolines
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623004496

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http://www.sciencedirect.com/science/article/pii/S2211715623004496

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